Transabdominal ultrasound elastography of the esophagogastric junction predicts reflux esophagitis

Hiroki Suhara, Yoshiki Hirooka, Hiroki Kawashima, Eizaburo Ohno, Takuya Ishikawa, Masanao Nakamura, Ryoji Miyahara, Masatoshi Ishigami, Senju Hashimoto, Hidemi Goto

研究成果: Article査読

2 被引用数 (Scopus)

抄録

Purpose: Abdominal ultrasound (US) can visualize the esophagogastric junction (EGJ) as a hyperechoic area in the dorsal portion of the lateral segment of the liver. We prospectively evaluated the EGJ using US elastography (US-EG) in patients with reflux esophagitis (RE) to examine prediction of distal esophageal function. Methods: Of 108 patients undergoing US-EG and esophagogastroduodenoscopy, 102 in whom the EGJ was observed for ≥ 15 s were included. The subjects were divided into a RE group (n = 41, Grade M/A/B:24/13/4 according to modified Los Angeles Classification) and a non-RE group (n = 61). Direct strain elastography (LOGIQ E9, GE Healthcare), which gives a semi-quantitative elasticity index within a region of interest including the lateral segment, was used as a standard for measurement of the change in stiffness (CS) at the EGJ. Results: The number of CS as determined by US-EG was 6.0 (5.5–6.7) in the RE group and 8.6 (6.6–10.0) in the non-RE group (P < 0.0001). In ROC analysis, the AUC was 0.8415 for diagnosis of RE using the number of CS. At a cut-off of 7.7, the sensitivity, specificity, and accuracy for diagnosis were 92.7, 65.6, and 74.5%, respectively. Conclusion: The presence of RE can be predicted based on US-EG.

本文言語English
ページ(範囲)99-104
ページ数6
ジャーナルJournal of Medical Ultrasonics
46
1
DOI
出版ステータスPublished - 25-01-2019
外部発表はい

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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