Transmission of chromosomally integrated human herpesvirus 6 via cord blood transplantation

Yuji Yamada; Tomoo Osumi; Ken Ichi Imadome; Etsuko Takahashi; Tamae Ohye; Tetsushi Yoshikawa; Daisuke Tomizawa; Motohiro Kato; Kimikazu Matsumoto

doi:10.1111/tid.12636

Transmission of chromosomally integrated human herpesvirus 6 via cord blood transplantation

Yuji Yamada, Tomoo Osumi, Ken Ichi Imadome, Etsuko Takahashi, Tamae Ohye, Tetsushi Yoshikawa, Daisuke Tomizawa, Motohiro Kato, Kimikazu Matsumoto

研究成果: Article › 査読

5 被引用数 (Scopus)

抄録

Chromosomally integrated human herpesvirus 6 (ciHHV-6) can be transmitted via allogeneic hematopoietic cell transplantation. To date, only a few cases have been reported. Here, we report a case identified as transmission of ciHHV-6 via cord blood transplantation. Distinguishing transmission of ciHHV-6 from HHV-6 reactivation in cases with high titer of HHV-6 DNA load after transplantation is important to prevent unnecessary exposure to antiviral drugs that could be toxic.

本文言語	English
論文番号	e12636
ジャーナル	Transplant Infectious Disease
巻	19
号	1
DOI	https://doi.org/10.1111/tid.12636
出版ステータス	Published - 01-02-2017

All Science Journal Classification (ASJC) codes

Infectious Diseases
Transplantation

文献へのアクセス

10.1111/tid.12636

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引用スタイル

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AU - Imadome, Ken Ichi

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AU - Ohye, Tamae

AU - Yoshikawa, Tetsushi

AU - Tomizawa, Daisuke

AU - Kato, Motohiro

AU - Matsumoto, Kimikazu

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AB - Chromosomally integrated human herpesvirus 6 (ciHHV-6) can be transmitted via allogeneic hematopoietic cell transplantation. To date, only a few cases have been reported. Here, we report a case identified as transmission of ciHHV-6 via cord blood transplantation. Distinguishing transmission of ciHHV-6 from HHV-6 reactivation in cases with high titer of HHV-6 DNA load after transplantation is important to prevent unnecessary exposure to antiviral drugs that could be toxic.

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