Treatment of solid tumor by a small amount of direct current

K. Ito, Chung Lin Ye Chung Lin, K. Kondou, S. Akiyama, H. Takagi, H. Hirota, T. Endo, G. Itoh, M. Suzuki, S. Ikeda

研究成果: Article

2 引用 (Scopus)

抜粋

Solid tumor treatment was given in our animal laboratory to determine the mechanism of tumor disappearance by direct electric current, and clinical trials were done on 9 far advanced recurrent rectal cancers. Solid tumors of Yoshida sarcoma in Donryu rat were treated by 1 mA of constant direct current for 1 hour a day, for 4 days. The tumors disappeared in 13/16 within 21 days. Positive results of DNA Nick end labeling and ladder patterns in the gel electrophoresis of DNA were observed in the regressing tumor specimen. It is considered that apoptosis is the one of the mechanisms of a disappearing tumor. As for the clinical trial concern, in 9 cases of rectal cancer, one CR and 5 PR were seen.

元の言語English
ページ(範囲)1647-1651
ページ数5
ジャーナルJapanese Journal of Cancer and Chemotherapy
22
発行部数11
出版物ステータスPublished - 1995

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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    Ito, K., Ye Chung Lin, C. L., Kondou, K., Akiyama, S., Takagi, H., Hirota, H., Endo, T., Itoh, G., Suzuki, M., & Ikeda, S. (1995). Treatment of solid tumor by a small amount of direct current. Japanese Journal of Cancer and Chemotherapy, 22(11), 1647-1651.