Treatment of solid tumor by a small amount of direct current

K. Ito, Chung Lin Ye Chung Lin, K. Kondou, S. Akiyama, H. Takagi, H. Hirota, T. Endo, G. Itoh, M. Suzuki, S. Ikeda

研究成果: ジャーナルへの寄稿学術論文査読

2 被引用数 (Scopus)

抄録

Solid tumor treatment was given in our animal laboratory to determine the mechanism of tumor disappearance by direct electric current, and clinical trials were done on 9 far advanced recurrent rectal cancers. Solid tumors of Yoshida sarcoma in Donryu rat were treated by 1 mA of constant direct current for 1 hour a day, for 4 days. The tumors disappeared in 13/16 within 21 days. Positive results of DNA Nick end labeling and ladder patterns in the gel electrophoresis of DNA were observed in the regressing tumor specimen. It is considered that apoptosis is the one of the mechanisms of a disappearing tumor. As for the clinical trial concern, in 9 cases of rectal cancer, one CR and 5 PR were seen.

本文言語英語
ページ(範囲)1647-1651
ページ数5
ジャーナルJapanese Journal of Cancer and Chemotherapy
22
11
出版ステータス出版済み - 1995
外部発表はい

All Science Journal Classification (ASJC) codes

  • 医学一般

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