Two cases of Stevens-Johnson syndrome analyzed for HLA

Masamichi Abe, Mamiko Nakagawa, Kayoko Matsunaga, Akiko Yagami, Akiyo Sano

研究成果: Article

抄録

We report two Japanese patients with Stevens-Johnson syndrome (SJS) who were investigated for HLA gene markers associated with SJS and toxic epidermal necrolysis. Patient 1 was a 53-year-old woman. She developed eruptions in oral provocation tests and was diagnosed with SJS due to allopurinol, clarithromycin, and loxoprofen sodium. Gene analysis revealed HLA-B*5801. Patient 2 was a 54-year-old man. He was positive on a carbamazepine patch test and drug-induced lymphocyte stimulation test, and was diagnosed with SJS due to carbamazepine. HLA-B*1502 was not detected on gene analysis.

元の言語English
ページ(範囲)158-163
ページ数6
ジャーナルSkin Research
8
発行部数2
出版物ステータスPublished - 01-04-2009
外部発表Yes

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Stevens-Johnson Syndrome
HLA-B Antigens
Carbamazepine
Genes
Allopurinol
Patch Tests
Clarithromycin
Lymphocyte Activation
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Dermatology
  • Infectious Diseases

これを引用

Abe, M., Nakagawa, M., Matsunaga, K., Yagami, A., & Sano, A. (2009). Two cases of Stevens-Johnson syndrome analyzed for HLA. Skin Research, 8(2), 158-163.
Abe, Masamichi ; Nakagawa, Mamiko ; Matsunaga, Kayoko ; Yagami, Akiko ; Sano, Akiyo. / Two cases of Stevens-Johnson syndrome analyzed for HLA. :: Skin Research. 2009 ; 巻 8, 番号 2. pp. 158-163.
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abstract = "We report two Japanese patients with Stevens-Johnson syndrome (SJS) who were investigated for HLA gene markers associated with SJS and toxic epidermal necrolysis. Patient 1 was a 53-year-old woman. She developed eruptions in oral provocation tests and was diagnosed with SJS due to allopurinol, clarithromycin, and loxoprofen sodium. Gene analysis revealed HLA-B*5801. Patient 2 was a 54-year-old man. He was positive on a carbamazepine patch test and drug-induced lymphocyte stimulation test, and was diagnosed with SJS due to carbamazepine. HLA-B*1502 was not detected on gene analysis.",
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Abe, M, Nakagawa, M, Matsunaga, K, Yagami, A & Sano, A 2009, 'Two cases of Stevens-Johnson syndrome analyzed for HLA', Skin Research, 巻. 8, 番号 2, pp. 158-163.

Two cases of Stevens-Johnson syndrome analyzed for HLA. / Abe, Masamichi; Nakagawa, Mamiko; Matsunaga, Kayoko; Yagami, Akiko; Sano, Akiyo.

:: Skin Research, 巻 8, 番号 2, 01.04.2009, p. 158-163.

研究成果: Article

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AB - We report two Japanese patients with Stevens-Johnson syndrome (SJS) who were investigated for HLA gene markers associated with SJS and toxic epidermal necrolysis. Patient 1 was a 53-year-old woman. She developed eruptions in oral provocation tests and was diagnosed with SJS due to allopurinol, clarithromycin, and loxoprofen sodium. Gene analysis revealed HLA-B*5801. Patient 2 was a 54-year-old man. He was positive on a carbamazepine patch test and drug-induced lymphocyte stimulation test, and was diagnosed with SJS due to carbamazepine. HLA-B*1502 was not detected on gene analysis.

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Abe M, Nakagawa M, Matsunaga K, Yagami A, Sano A. Two cases of Stevens-Johnson syndrome analyzed for HLA. Skin Research. 2009 4 1;8(2):158-163.