Two patients with familial hypercholesterolemia who were successfully weaned from low-density lipoprotein apheresis after treatment with evolocumab

Akihito Tanaka, Daijo Inaguma, Yu Watanabe, Eri Ito, Naoki Kamegai, Hiroya Shimogushi, Hibiki Shinjo, Kiyomi Koike, Yasuhiro Otsuka, Asami Takeda

研究成果: Article

抜粋

Two elderly patients (a 76-year-old man and a 75-year-old woman), who had been previously diagnosed with familial hypercholesterolemia (at 58 and 48 years of age, respectively) underwent long-term treatment with oral therapy and low-density lipoprotein (LDL) apheresis. As their LDL cholesterol levels remained high (>150 mg/dL and >120 mg/dL, respectively) and their familial hypercholesterolemia was complicated with angina pectoris, we added evolocumab to their prescription. Thereafter, their LDL cholesterol levels decreased rapidly, and the patients were successfully weaned from LDL apheresis. Evolocumab therapy should thus be considered when LDL apheresis cannot achieve the target LDL cholesterol levels, though the prognosis of such treatment remains unclear.

元の言語English
ページ(範囲)1531-1535
ページ数5
ジャーナルInternal Medicine
56
発行部数12
DOI
出版物ステータスPublished - 2017
外部発表Yes

All Science Journal Classification (ASJC) codes

  • Internal Medicine

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