Urinary protein to creatinine ratio and urinary sediments are useful for the screening of chronic kidney disease

Saori Kobayashi, Masato Hoshi, Isao Inagaki, Takayuki Hattori, Seiko Ushimaru, Hazuki Ohashi, Nobuyuki Furuta, Masao Marumoto, Masao Takemura, Hiroyasu Ito, Mitsuru Seishima

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Chronic Kidney Disease (CKD) is an important risk factor of the End Stage Renal Disease (ESRD). In this study, we investigated whether the protein to creatinine ratio (the ratio of P/C) determined by the semiquantitative urinary stick test and urinary sediments are useful for the early detection of CKD. One hundred sixty patients were classified to four or five groups by P/C ratio and various biochemical markers were analyzed. As a result, the 300 mg/g x Cr of P/C group showed a significantly increased serum cystatin C level. The positive rate of the P/C ratio in CKD stage was significantly increased compared with the conventional protein qualitative analysis. Further, the amounts of urinary sediments in CKD stage 1 to 2 were increased, such as hyaline cast, and pathological casts were increased in CKD stage 3 to 5. Thus, our present study suggests that the ratio of P/C and urinary sediments are useful for the screening of CKD.

本文言語English
ページ(範囲)213-220
ページ数8
ジャーナルRinsho byori. The Japanese journal of clinical pathology
57
3
出版ステータスPublished - 03-2009
外部発表はい

All Science Journal Classification (ASJC) codes

  • 医学(全般)

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