Usefulness of contrast-enhanced ultrasonography in the differential diagnosis of polypoid gallbladder lesions

Masashi Hattori, Kazuo Inui, Junji Yoshino, Hironao Miyoshi, Kazumu Okushima, Yuta Nakamura, Takehito Naito, Yoshihiro Imaeda, Yoshimune Horibe, Toshiyuki Hattori, Saburou Nakazawa

研究成果: Article査読

23 被引用数 (Scopus)

抄録

We investigated the usefulness of contrast-enhanced ultrasonography for differential diagnosis of polypoid gallbladder lesions in 60 patients, consisting of gallbladder carcinoma in 20, adenoma in 2, benign polyp in 29, and adenomyomatosis in 9, comparing contrast enhancement patterns with pathologic findings. We monitored vascular flow for 120 sec, constructing a time intensity curve (TIC) by flash-echo imaging. We compared the number of vessels and vessel diameter determined by contrast enhancement patterns and by pathologic examination. Contrast enhancement patterns were classified as linear, scattered, diffuse, or branched. When diffuse type and branched type were considered as indicative of cancer, accuracy was 84.5%, sensitivity 100%, and specificity 76.9%. In gallbladder carcinoma, the TIC rose from no contrast to early-phase contrast sooner than in other diseases. In adenocarcinoma, high-intensity values persisted at 120 sec. With an intensity of 90 or greater at 120 sec taken as indicating cancer, accuracy was 89.7%, sensitivity 89.5%, and specificity 89.7%; Vessels were significantly more numerous in diffuse type cases than in those with other patterns. Vessel diameter was greatest in the diffuse type and the branched type patterns, both differing significantly from the linear type. Ultrasonographic contrast enhancement patterns show characteristic associations with pathologic findings and serve as valuable adjuncts in the diagnosis of gallbladder diseases.

本文言語English
ページ(範囲)790-798
ページ数9
ジャーナルJapanese Journal of Gastroenterology
104
6
出版ステータスPublished - 06-2007

All Science Journal Classification (ASJC) codes

  • 消化器病学

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