TY - JOUR
T1 - Utility of intraoperative real-time near-infrared fluorescence surgery for spinal schwannoma
AU - Muto, Jun
AU - Mine, Yutaka
AU - Nagai, Sota
AU - Shizu, Naoyuki
AU - Takeda, Hiroki
AU - Ikeda, Daiki
AU - Saito, Akifumi
AU - Joko, Masahiro
AU - Hasegawa, Mitsuhiro
AU - Kaneko, Shinjiro
AU - Inoue, Tatsushi
AU - Lee, John Y.K.
AU - Hirose, Yuichi
N1 - Publisher Copyright:
© 2022 The authors.
PY - 2022/1
Y1 - 2022/1
N2 - The authors report the first cases of fluorescence-guided spinal surgery of schwannomas using near-infrared fluorescence imaging with the delayed window indocyanine (ICG) green (DWIG) technique for accurate real-time intraoperative tumor visualization. Patients with intradural spinal schwannomas received 0.5 mg/kg ICG at the beginning of surgery. After 1 hour, using the DWIG technique, near-infrared spectroscopy (NIRS) detected the spinal schwannomas, showing the exact tumor location and boundaries. DWIG with NIRS microscopy confirmed the exact location of spinal schwannomas before and after opening of the dura mater, thereby facilitating successful tumor dissection from the surrounding tissues, tumor resection, and confirmation of tumor removal.
AB - The authors report the first cases of fluorescence-guided spinal surgery of schwannomas using near-infrared fluorescence imaging with the delayed window indocyanine (ICG) green (DWIG) technique for accurate real-time intraoperative tumor visualization. Patients with intradural spinal schwannomas received 0.5 mg/kg ICG at the beginning of surgery. After 1 hour, using the DWIG technique, near-infrared spectroscopy (NIRS) detected the spinal schwannomas, showing the exact tumor location and boundaries. DWIG with NIRS microscopy confirmed the exact location of spinal schwannomas before and after opening of the dura mater, thereby facilitating successful tumor dissection from the surrounding tissues, tumor resection, and confirmation of tumor removal.
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U2 - 10.3171/2021.10.FOCVID21158
DO - 10.3171/2021.10.FOCVID21158
M3 - Article
AN - SCOPUS:85144861589
SN - 2643-5217
VL - 6
JO - Neurosurgical Focus: Video
JF - Neurosurgical Focus: Video
IS - 1
ER -