Vitamin E and coenzyme Q concentrations in the thyroid tissues of patients with various thyroid disorders

Toshiki Mano, Katumi Iwase, Ritsuko Hayashi, Nobuki Hayakawa, Keiko Uchimura, Masaki Makino, Mutsuko Nagata, Yosikuni Sawai, Naohisa Oda, Michiko Hamada, Toshihiro Aono, Akira Nakai, Akio Nagasaka, Mitsuyasu Itoh

研究成果: Article査読

15 被引用数 (Scopus)

抄録

To clarify the different roles of free radical scavenging systems in various thyroid disorders, we measured the levels of α-, β-, and γ- tocopherols and coenzyme Q in the thyroid tissues of patients with thyroid tumors and Graves' disease using high-performance liquid chromatography. The levels of α-tocopherols and γ-tocopherols in the thyroid tissue of patients with papillary carcinoma and the level of γ-tocopherol in the thyroid tissue of patients with malignant lymphoma were elevated compared with those in normal thyroid tissues. The level of coenzyme Q was reduced in the thyroid tissue of patients with Graves' disease and follicular and papillary thyroid carcinomas. These findings imply that vitamin E and coenzyme Q as scavengers play some role in thyroid follicular cell hyperfunction or dysfunction.

本文言語English
ページ(範囲)230-232
ページ数3
ジャーナルAmerican Journal of the Medical Sciences
315
4
DOI
出版ステータスPublished - 01-01-1998

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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