Vomeroglandin/CRP-ductin is strongly expressed in the glands associated with the mouse vomeronasal organ: Identification and characterization of mouse vomeroglandin

Fumio Matsushita, Atsushi Miyawaki, Katsuhiko Mikoshiba

研究成果: Article査読

30 被引用数 (Scopus)

抄録

Vomeroglandin, a subform of mouse CRP-ductin, is a protein strongly expressed in the glands of mouse vomeronasal system. Both the proteins contain several of scavenger receptor cysteine-rich and CUB domains and one ZP domain. This domain arrangement is similar to those of rat Ebnerin, human DMBT1, and rabbit hensin. In situ hybridization analysis shows strong expression of vomeroglandin mRNA in the glands of vomeronasal system. Immunological analyses detect both membrane-bound and secreted forms of vomeroglandin. The secreted protein seems to be localized in the lumen of the vomeronasal organ, playing a certain role in the pheromone perception. (C) 2000 Academic Press.

本文言語English
ページ(範囲)275-281
ページ数7
ジャーナルBiochemical and Biophysical Research Communications
268
2
DOI
出版ステータスPublished - 16-02-2000
外部発表はい

All Science Journal Classification (ASJC) codes

  • 生物理学
  • 生化学
  • 分子生物学
  • 細胞生物学

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